Plasma membrane cholesterol trafficking in steroidogenesis
نویسندگان
چکیده
منابع مشابه
STARD3/MLN64 is Striving at Membrane Contact Sites: Intracellular Cholesterol Trafficking for Steroidogenesis in Human Placental Cells
Steroid hormone synthesis begins with the conversion of cholesterol into pregnenolone by the enzyme cytochrome P450scc in mitochondria. The cholesterol used to synthesize pregnenolone is derived mainly from endocytosed LDL cholesterol. How this LDL cholesterol is transported to mitochondria in the human placenta is not well understood. Recent work has focused on how STARD3/MLN64 controls choles...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2018
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fj.201800697rrr